The CIF offers four open-access solution NMR spectrometers, and one cryoprobe-equipped spectrometer that is available for special projects. Below is a comparison of the currently available sensitivity and lineshape values for each spectrometer. Other considerations when choosing a spectrometer include available nuclei, available pulse sequences, requirements for 19F or 1H decoupling, and variable temperature limits. This page is only meant to be a guide in selecting in an instrument. Don't hesitate to ask if you still have questions about selecting the best spectrometer for your project.
Spectrometer Features
| Spectrometer | Probe | Temp Range | BB Tune Range | Feature 1 | Feature 2 | Feature 3 | Feature 4 |
|---|
| AVIIIHD300 | BBFO | +25 to 150 °C | 97Mo - 31P, 19F | 19F on BB | Autotune | Autosampler | VT to +150 °C |
| MR400 | OneNMR | -80 to +130 °C | 15N - 31P | 19F/ 1H shared | Autotune | Expt Queue | No VT |
| NEO400 cryo | Prodigy | -40 to +80 °C | 15N - 31P | 19F/ 1H shared | Autotune | Autosampler | Chiller to ~ -10 °C |
| AVIII600 | BBFO* | -150 to +150 °C | 109Ag - 31P, 19F | 19F on BB | Autotune | Autosampler | Chiller + LN2 exchanger |
| AVIII600 | TBI | -150 to +150 °C | 109Ag - 31P | 19F/ 1H shared | No Autotune | Autosampler | 1H/13C/BB for 13C dec |
| AVII600 cryo | QCI-P | 0 to +135 °C | 1H,13C,15N,31P | 1H fixed | Autotune | Fixed Freq | Highest sensitivity |
*BBFO probe is typically installed on the AVIII600
1H Resolution and Lineshape - Current Values - 1% Chloroform in Acetone-D6
| Spectrometer | Date of Acq | Nucleus | 50% (in Hz) | 0.55% (in Hz) | 0.11% (in Hz) | Remarks |
|---|
| AVIIIHD300 | 10/1/25 | 1H | 0.5 | 4.3 | 13.7 | w/o rotation |
| MR400 | 7/16/19 | 1H | 0.6 | 6 | 10 | w/o rotation |
| NEO400 Cryo | 4/18/19 | 1H | 0.4 | 3 | 6 | w/o rotation |
| AVIII600 | 9/4/25 | 1H | 0.9 | 8 | 22 | w/o rotation |
| AVIII600 Cryo | 4/28/25 | 1H | 0.6 | 9 | 13 | w/o rotation |
1H and 13C Sensitivity - Current Values - Ethylbenzene in CDCl3
| Spectrometer | Date of Acq | Nucleus | Sample | Signal to Noise | Remarks |
|---|
| AVIIIHD300 | 10/1/25 | 1H | 0.1% Ethylbenzene in CDCl3 | 238 | rotation |
| AVIIIHD300 | 10/1/25 | 13C | 10% Ethylbenzene in CDCl3 | 122 | rotation |
| MR400 | 7/17/19 | 1H | 0.1% Ethylbenzene in CDCl3 | 376 | rotation / without rotation |
| MR400 | 7/17/19 | 13C | 10% Ethylbenzene in CDCl3 | 181 | rotation / without rotation |
| NEO400 Cryo | 4/18/19 | 1H | 0.1% Ethylbenzene in CDCl3 | 1043 / 1030 | rotation / without rotation |
| NEO400 Cryo | 4/18/19 | 13C | 10% Ethylbenzene in CDCl3 | 513 / 435 | rotation / without rotation |
| AVIII600 | 4/18/19 | 1H | 0.1% Ethylbenzene in CDCl3 | 764 / 725 | rotation / without rotation |
| AVIII600 | 4/18/19 | 13C | 10% Ethylbenzene in CDCl3 | 343 / 283 | rotation / without rotation |
| AVII600 Cryo | 10/7/25 | 1H | 0.1% Ethylbenzene in CDCl3 | 2734 / 2647 | rotation / without rotation |
| AVII600 Cryo | 9/27/19 | 13C | 10% Ethylbenzene in CDCl3 | 982 / 926 | rotation / without rotation |
